My strategy is if I am on a busy highway, I will plug the tire quickly to get off the road if the tire is able to be plugged. I will then drive to a safer place to swap to the spare. I will have the tire repaired with a internal patch at a tire place ASAP.
For me, its all about getting off the side of the road on a busy highway quickly. Frequently someone is killed where I live on the side of the highway. I also have a safety vest and safety triangles.
As far as learning how to use a tire plug, there are many of You Tube videos that show you have to do this. Just Google, using a tire plug kit. Here is one video,
Here is the plug kit I purchased. Perhaps there are better ones but this one seemed to fit the bill for my needs.
TOOLUXE 50002L -35 Piece Tire Repair Universal Heavy Duty Tire Repair Kit with Plugs, Fix A Flat Tire Repair Kit, Ideal for Tires on Cars, Trucks, Motorcycles, ATV Roadside Emergency, Tire Plug Kit - Hand Tool Sets - Amazon.com
Check the air pressure in your spare every six months or so. They do loose pressure and you want it to be ready if you need it.
You also want to consider purchasing an air pump. Even if you plug a tire on the side of the road, it most likely will be way under inflated.
You have three different choices for an air pump.
One that plugs into a 12 volt cigarette lighter socket. I do not recommend this type as some will blow fuses.
Here is an example,
Campbell Hausfeld Mighty 150 PSI Lightweight 12V Portable Inflator with Safety Light and Inflation Accessories AF010400 - The Home Depot
One that connects directly to the car's 12 volt battery. I like this type but it does take extra time to use.
Here is example,
Amazon.com: VIAIR 88P - 00088 Tire Inflator Portable Onroad/Offroad Air Compressor for Car, Truck, SUV & RV | 12V On/Off Road Tire Pump Air Compressor Portable Heavy Duty 120 PSI, Alligator Clips, Twist Chuck : Viair: Automotive
One that uses a cordless tool battery. I like this type because it is quick to deploy but can be slow filing a tire and one needs to remember to charge the battery. Some also are able to be powered as a back up by a 12 volt cigarette lighter socket. If you already one cordless tools, check to see if your manufacture makes an air pump so you have extra batteries.
Here is an example,
The 18V Digital Inflator features a Rotating Digital Dial, a Quick Connect Air Chuck, and Auto-Shutoff.
www.ridgid.com